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- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for Type I Collagen Antibody (OASB02738) |
|---|
| Tested Species Reactivity | Human |
|---|---|
| Predicted Species Reactivity | Mouse, Rat, Bovine, Canine, Chicken, Chinchilla, Elephant, Feline, Guinea Pig, Hamster, Porcine, Rabbit, Sheep, Tree Shrew |
| Product Format | Liquid Borate buffered saline (pH 8.2) |
| Clonality | Polyclonal |
| Host | Goat |
| Conjugation | Unconjugated |
| Application | EM, FC, ICC, IHC-F, IHC-P, IP, WB |
| Reconstitution and Storage | Store at 2-8°C |
| Purification | Purified by affinity chromatography on type I collagen covalently linked to agarose. |
| Concentration | 0.4 mg/mL |
| Specificity | Reacts with conformational determinants on type I collagen; cross-adsorbed against Collagen types II, III, IV, V, and VI for minimal reactivity. |
| Source | Pooled antisera from goats hyperimmunized with type I collagen |
| Gene Symbol | COL1A1, COL1A2 |
|---|---|
| Gene Full Name | collagen type I alpha 1 chain |
| Alias Symbols | OI1, OI2, OI3, OI4, EDSC, CAFYD, EDSARTH1 |
| NCBI Gene Id | 1277; 1278 |
| Protein Name | collagen alpha-1(I) chain |
| Description of Target | This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. |
| Uniprot ID | P02452, P08123 |
| Protein Accession # | NP_000079.2 |
| Nucleotide Accession # | NM_000088.3 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Type I Collagen Antibody (OASB02738)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Mouse, Rat, Bovine, Canine, Chicken, Chinchilla, Elephant, Feline, Guinea Pig, Hamster, Porcine, Rabbit, Sheep, Tree Shrew".
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How long will it take to receive "Type I Collagen Antibody (OASB02738)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "Type I Collagen Antibody (OASB02738)" provided in?
This item is provided in "Liquid Borate buffered saline (pH 8.2) ".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Type I Collagen Antibody (OASB02738)"?
This target may also be called "OI1, OI2, OI3, OI4, EDSC, CAFYD, EDSARTH1" in publications.
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What is the shipping cost for "Type I Collagen Antibody (OASB02738)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Type I Collagen Antibody (OASB02738)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Type I Collagen Antibody (OASB02738)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Type I Collagen Antibody (OASB02738)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "COL1A1, COL1A2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "COL1A1, COL1A2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "COL1A1, COL1A2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "COL1A1, COL1A2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "COL1A1, COL1A2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "COL1A1, COL1A2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.