GDF15 Recombinant Protein (OPCD03492)

Catalog No: OPCD03492

GDF15 Recombinant Protein (OPCD03492) using SDS-PAGE

GDF15 Recombinant Protein (OPCD03492) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Rat|Rattus norvegicus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ser189-Ala303
  Subcellular Location: Secreted
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 97%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Gdf15
• Gene Full Name: growth differentiation factor 15
• Alias Symbols: GDF-15;growth/differentiation factor 15.
• NCBI Gene Id: 29455
• Protein Name: Growth/differentiation factor 15
• Description of Target: egulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem. It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (Probable). On hepatocytes, inhibits growth hormone signaling (By similarity).
• Uniprot ID: Q9Z0J6
• Protein Accession #: NP_062089.1
• Nucleotide Accession #: NM_019216.2
• Protein Size (# AA): Ser189~Ala303
• Molecular Weight: 16kDa