Flt3 Ligand Protein (OPPA01980)

Catalog No: OPPA01980 (Formerly GWB-7D55D0)

Size:2UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: The protein was lyophilized with no additives. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
• Host: HEK293 (Human Embryonic Kidney Cell Line)
• Additional Information: Solubility: It is recommended to reconstitute the lyophilized Flt3-Ligand in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
  Biological Activity: The ED50 as determined by the dose dependent proliferation of human OCI-AML5 cells is 0.5 to 1.0 ng/ml (Specific Activity: 2.0 x 1,000,000 - 1.0 x 1,000,000 units/mg).
  Product Introduction: FLT3 ligand is a receptor for the fl cytokine has a tyrosine-protein kinase activity & a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand synergizes with other CSFs and interleukins to induce growth and differentiation.
  Product Description: Flt3-Ligand Human Recombinant produced in HEK293 cells is a glycosylated, polypeptide chain, migrates as a diffuse band on SDS-PAGE due to heterogeneous glycosylation at 30kDa. Flt3-Ligand is purified by proprietary chromatographic techniques.
• Reconstitution and Storage: Lyophilized Flt3-Ligand although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution Flt3-Ligand should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please prevent freeze-thaw cycles.
• Purity: Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
• Peptide Sequence: TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTAPQP.
• Source: HEK293 Cells

Target Info

• Gene Symbol: Flt3 Ligand, HEK
• Alias Symbols: FL, FLG3L, FLT3L
• NCBI Gene Id: 2323
• Protein Name: Fms-related tyrosine kinase 3 ligand
• Description of Target: Recombinant Human Flt3-Ligand, HEK
• Uniprot ID: P49771
• Protein Accession #: NP_001450.2
• Protein Size (# AA): Recombinant