FAM120A Antibody (OAPB00943)

Catalog No: OAPB00943

Size:100UG

Western blot analysis of FAM120A in SK-N-SH cell lysate with FAM120A antibody at (A) 0.5 and (B) 1 ug/mL.

Immunohistochemistry of FAM120A in rat brain tissue with FAM120A antibody at 2.5 ug/mL.

Product Info

• Predicted Species Reactivity: Bovine|Human|Mouse|Rat
• Product Format: Liquid. FAM120A Antibody is supplied in PBS containing 0.02% sodium azide.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: FAM120A antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Immunogen: FAM120A antibody was raised against an 18 amino acid synthetic peptide from near the center of human FAM120A. The immunogen is located within amino acids 610 - 660 of FAM120A.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human; Mouse; Rat
• Concentration: 1 mg/ml
• Blocking Peptide: For anti-FAM120A antibody is Catalog # OEPB03063
• Application Info: FAM120A antibody can be used for detection of FAM120A by Western blot at 0.5 - 1 ug/ml. (Optimal dilution should be determined by user)
• Reference: Holden S and Raymond FL. The human gene CXorf17 encodes a member of a novel family of putative transmembrane proteins: cDNA cloning and characterization of CXorf17 and its mouse ortholog orf34. Gene2003; 318:149-61.;Kobayashi Y, Suzuki K, Kobayashi H, et al. C9orf10 protein, a novel protein component of Puralpha-containing mRNA-protein particles (Puralpha-mRNPs): characterization of developmental and regional expressions in the mouse brain. J. Histochem. Cytochem.2008; 56:723-31. ;Tanaka M, Sasaki K, Kamata R, et al. A novel RNA-binding protein, Ossa/C9orf10, regulates activity of Src kinases to protect cells from oxidative stress-induced apoptosis. Mol. Cell. Biol.2009; 29:402-13.;

Target Info

• Gene Symbol: FAM120A
• Gene Full Name: family with sequence similarity 120A
• Alias Symbols: C9orf10;constitutive coactivator of PPAR-gamma-like protein 1;HBVPTPAP;OSSA;oxidative stess-associated Src activator;oxidative stress-associated Src activator;Protein FAM120A.
• NCBI Gene Id: 23196
• Protein Name: Constitutive coactivator of PPAR-gamma-like protein 1|constitutive coactivator of PPAR-gamma-like protein 1 isoform a [Homo sapiens]
• Description of Target: May participate in mRNA transport in the cytoplasm (By similarity). Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.
• Uniprot ID: Q9NZB2
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_055427