EVER1 Antibody (OAPB00659)

Catalog No: OAPB00659

Size:100UG

Western blot analysis of EVER1 in human spleen tissue lysate with EVER1 antibody at (A) 1 and (B) 2 ug/mL.

Immunohistochemistry of EVER1 in human spleen with EVER1 antibody at 2.5 ug/mL.

Product Info

• Predicted Species Reactivity: Human|Mouse
• Product Format: Liquid. EVER1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: EVER1 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Immunogen: EVER1 antibody was raised against a 15 amino acid synthetic peptide from near the center of human EVER1. The immunogen is located within amino acids 560 - 610 of EVER1.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human; Mouse
• Concentration: 1 mg/ml
• Blocking Peptide: For anti-EVER1 antibody is Catalog # OEPB02774
• Application Info: EVER1 antibody can be used for the detection of EVER1 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
• Reference: Majewski S, Jablonska J and Orth G. Epidermodysplasia verruciformis. Immunological and nonimmunological surveillance mechanisms: role in tumor progression. Clin. Dermatol.1997; 15:321-34. ;Ramoz N, Rueda L-A, Bouadjar B, et al. Mutations in two adjacent novel genes are associated with epidermodysplasia verruciformis. Nat. Genetics2002; 32:579-81.;Keresztes G, Mutai H and Heller S. TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins. BMC Genomics2003; 4:24-34.;Lazarczyk L, Pons C, Mendoza JA, et al. Regulation of cellular zinc balance as a potential mechanism of EVER-mediated protection against pathogenesis by cutaneous oncogenic human papillomaviruses. J. Exp. Med.2008; 205:35-42.

Target Info

• Gene Symbol: TMC6
• Gene Full Name: transmembrane channel like 6
• Alias Symbols: epidermodysplasia verruciformis 1;epidermodysplasia verruciformis protein 1;EV1;EVER1;EVIN1;expressed in activated T/LAK lymphocytes;LAK-4P;lnc;protein LAK-4;TNRC6C antisense RNA 1;TNRC6C-AS1;transmembrane channel-like protein 6.
• NCBI Gene Id: 11322
• Protein Name: large EVER1 protein [Homo sapiens]|Transmembrane channel-like protein 6
• Description of Target: Probable ion channel.
• Uniprot ID: Q7Z403
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/AAM44452