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Datasheets/Manuals | Printable datasheet for anti-EIF4EBP1 (OAEC04315) antibody |
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Predicted Species Reactivity | Human |
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Product Format | Ascitic fluid containing 0.03% sodium azide |
Clonality | Monoclonal |
Clone | 11G12C11 |
Isotype | IgG1 |
Host | Mouse |
Application | IF, IHC |
Reconstitution and Storage | Store at 4C, for long term storage, store at -20C. |
Immunogen | Purified recombinant fragment of 4EBP1 expres sed in EColi. |
Concentration | 1 mg/ml |
Application Info | IF: 1/200 - 1/1000 IHC: 1/200 - 1/1000 ELISA: 1/10000 |
Gene Symbol | EIF4EBP1 |
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Gene Full Name | eukaryotic translation initiation factor 4E binding protein 1 |
Alias Symbols | BP-1, 4EBP1, 4E-BP1, PHAS-I |
NCBI Gene Id | 1978 |
Description of Target | 4E-BP1(eukaryotic translation Initiation Factor 4E Binding Protein 1), also called ELF4EBP1/BP-1/PHAS-I , which is located on chromosome 8p12, with 118-amino acid protein (about 13kDa). Binding of eIF4EBP1 to eIF4E is revers ible and is dependent on the phosphorylation status of eIF4EBP1. Non phosphorylated eIF4EBP1 will bind strongly to eIF4E while(24kDa), the phosphorylated form will not. Akt, TOR, MAP kinase, S6 kinase, and Cdc2 are known kinases capable of inactivating eIF4EBP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64. Although, not all phosphorylation events equally block the eIF4EBP1-eIF4E interaction. |
Uniprot ID | Q13541 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "EIF4EBP1 Antibody (OAEC04315)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "EIF4EBP1 Antibody (OAEC04315)"?
This item is available "Domestic: within 2-3 weeks delivery | International: 2-3 weeks".
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What buffer format is "EIF4EBP1 Antibody (OAEC04315)" provided in?
This item is provided in "Ascitic fluid containing 0.03% sodium azide".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "EIF4EBP1 Antibody (OAEC04315)"?
This target may also be called "BP-1, 4EBP1, 4E-BP1, PHAS-I" in publications.
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What is the shipping cost for "EIF4EBP1 Antibody (OAEC04315)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "EIF4EBP1 Antibody (OAEC04315)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "EIF4EBP1 Antibody (OAEC04315)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "EIF4EBP1 Antibody (OAEC04315)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "EIF4EBP1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "EIF4EBP1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "EIF4EBP1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "EIF4EBP1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "EIF4EBP1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "EIF4EBP1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.