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Catalog No: OAAF01784 (Formerly GWB-ASD059)
Size:100 ug
Price: $344.00
SKU
OAAF01784
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for EFNB3 Antibody (OAAF01784)
Product Info
Predicted Species ReactivityHuman|Mouse|Rat
Product FormatLiquid
ClonalityPolyclonal
HostRabbit
ApplicationEnzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Reconstitution and Storage-20°C
ImmunogenThe antiserum was produced against synthesized peptide derived from human EFNB3.
PurificationThe antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
SpecificityEFNB3 antibody detects endogenous levels of total EFNB3 protein.
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
DilutionThe optimal working dilution should be determined by the end user.
Application InfoWB: 1:500~1:1000; IHC: 1:50~1:100; ELISA: 1:20000
ReferenceMitsutoshi Nakada, Cancer Res., Sep 2006; 66: 8492 - 8500.
Klas Kullander, Genes & Dev., Apr 2001; 15: 877.
M. Douglas Benson, PNAS, Jul 2005; 102: 10694 - 10699.
Stephanie R. Kadison, J. Neurosci., Aug 2006; 26: 8909 - 8914.
Publications

Estrogen and testosterone in concert with EFNB3 regulate vascular smooth muscle cell contractility and blood pressure. Am J Physiol Heart Circ Physiol. 310, H861-72 (2016). 26851246

Description
Gene SymbolEFNB3
Gene Full Nameephrin B3
Alias SymbolsEFL6;EPH-related receptor transmembrane ligand ELK-L3;eph-related receptor tyrosine kinase ligand 8;ephrin-B3;EPLG8;LERK8.
NCBI Gene Id1949
Protein NameEphrin-B3
Description of TargetCell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity).
Uniprot IDQ15768
Protein Accession #NP_001397.1
Molecular Weight35 kDa
  1. What is the species homology for "EFNB3 Antibody (OAAF01784)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".

  2. How long will it take to receive "EFNB3 Antibody (OAAF01784)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "EFNB3 Antibody (OAAF01784)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "EFNB3 Antibody (OAAF01784)"?

    This target may also be called "EFL6;EPH-related receptor transmembrane ligand ELK-L3;eph-related receptor tyrosine kinase ligand 8;ephrin-B3;EPLG8;LERK8." in publications.

  5. What is the shipping cost for "EFNB3 Antibody (OAAF01784)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "EFNB3 Antibody (OAAF01784)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "EFNB3 Antibody (OAAF01784)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "35 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "EFNB3 Antibody (OAAF01784)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "EFNB3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "EFNB3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "EFNB3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "EFNB3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "EFNB3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "EFNB3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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