DBI Antibody - middle region (OASG00137)

Catalog No: OASG00137

Size:100 uL

Western Blot using HUVEC

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from the Internal region of human ACBP.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: ACBP Polyclonal Antibody detects endogenous levels of ACBP protein.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;

Target Info

• Gene Symbol: DBI
• Gene Full Name: diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
• Alias Symbols: EP, ACBP, ACBD1, CCK-RP
• NCBI Gene Id: 1622;
• Description of Target: This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.
• Uniprot ID: P07108
• Molecular Weight: 10 kDa