CSRP3 Antibody - middle region (ARP34181_P050)

Size:100 ul

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Human Heart

Human HCT116 Whole Cell

Basic Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CSRP3
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
• Complete computational species homology data: Anti-CSRP3 (ARP34181_P050)
• Peptide Sequence: Synthetic peptide located within the following region: QGAGCLSTDTGEHLGLQFQQSPKPARSVTTSNPSKFTAKFGESEKCPRCG
• Concentration: Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
• Blocking Peptide: For anti-CSRP3 (ARP34181_P050) antibody is Catalog # AAP34181 (Previous Catalog # AAPP05443)
• Datasheets/Manuals: Printable datasheet for anti-CSRP3 (ARP34181_P050) antibody
• Target Reference: Geier,C., et al., (2003) Circulation 107 (10), 1390-1395
• Publications:

  Roberts, M. D., Childs, T. E., Brown, J. D., Davis, J. W. & Booth, F. W. Early depression of Ankrd2 and Csrp3 mRNAs in the polyribosomal and whole tissue fractions in skeletal muscle with decreased voluntary running. J. Appl. Physiol. 112, 1291-9 (2012). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 22282489

Target Info

• Gene Symbol: CSRP3
• Official Gene Full Name: Cysteine and glycine-rich protein 3 (cardiac LIM protein)
• Alias Symbols: CLP, MLP, CRP3, LMO4, CMD1M, CMH12
• NCBI Gene Id: 8048
• Protein Name: Cysteine and glycine-rich protein 3
• Description of Target: The CSRP3 gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in CSRP3 are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans.
• Swissprot Id: P50461
• Protein Accession #: NP_003467
• Nucleotide Accession #: NM_003476
• Protein Size (# AA): 194
• Molecular Weight: 21kDa
• Tissue Tool: Find tissues and cell lines supported by DNA array analysis to express CSRP3.
• RNA Seq: Find tissues and cell lines supported by RNA-seq analysis to express CSRP3.
• Protein Interactions: UBC; HDAC4; LDHD; SPTB; NHLH1; MYF6; MYOG; MYOD1; ACTN1;