Size:100 tests
$230.00
In Stock
SKU
OAEE00727
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More Information
Predicted Species Reactivity Human, Porcine, Bovine, Dog
Clonality Monoclonal
Clone LT21
Isotype IgG1
Host Mouse
Application FC, IHC-F
Reconstitution and Storage Store in the dark at 2-8C. Do not freeze. Avoid prolonged exposure to light.
Do not use after expiration date stamped on vial label.
Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.
Replacement Item This antibody may replace item sc-13135 from Santa Cruz Biotechnology.
Immunogen IM9 human B-lymphoblastoid cell line
Purification Purified by size-exclusion chromatography
Concentration 20 ul / test
Datasheets/Manuals Printable datasheet for anti-CR2 (OAEE00727) antibody
Specificity The antibody LT21 reacts with CD21 (CR2), a 145 kDa transmembrane glycoprotein (complement C3d receptor - C3dR) expressed on B lymphocytes, follicular dendritic cells, some epithelial cells and a subsets of T lymphocytes. It is not expressed on immature B cells.
HLDA VI; WS Code B CD21.1
Formulation FITC
Storage Buffer The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
Target Reference Filatov AV, Krotov GI, Zgoda VG, Volkov Y: Fluorescent immunoprecipitation analysis of cell surface proteins: a methodology compatible with mass-spectrometry. J Immunol Methods. 2007 Jan 30;319(1-2):21-33.
Faldyna M, Samankova P, Leva L, Cerny J, Oujezdska J, Rehakova Z, Sinkora J: Cross-reactive anti-human monoclonal antibodies as a tool for B-cell identification in dogs and pigs. Vet Immunol Immunopathol. 2007 Sep 15;119(1-2):56-62.
Leukocyte Typing VI., Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997).
Singh A, Blank M, Shoenfeld Y, Illges H: Antiphospholipid syndrome patients display reduced titers of soluble CD21 in their sera irrespective of circulating anti-beta2-glycoprotein-I autoantibodies. Rheumatol Int. 2008 Jan 3
Zabel MD, Heikenwalder M, Prinz M, Arrighi I, Schwarz P, Kranich J, von Teichman A, Haas KM, Zeller N, Tedder TF, Weis JH, Aguzzi A: Stromal complement receptor CD21/35 facilitates lymphoid prion colonization andpathogenesis. J Immunol. 2007 Nov 1;179(9):6144-52.
Kasprzak A, Spachacz R, Wachowiak J, Stefanska K, Zabel M: Epstein-Barr virus (EBV) infection in B-cell non-Hodgkin's lymphomas in children: virus latency and its correlation with CD21 and CD23 molecules. Folia Histochem Cytobiol. 2007;45(3):169-79.
Twohig J, Kulik L, Haluszczak C, Reuter J, Rossbach A, Bull M, Holers VM, Marchbank KJ: Defective B cell ontogeny and immune response in human complement receptor 2 (CR2, CD21) transgenic mice is partially recovered in the absence of C3. Mol Immunol. 2007 Jul;44(13):3434-44.
Roozendaal R, Carroll MC: Complement receptors CD21 and CD35 in humoral immunity. Immunol Rev. 2007 Oct;219:157-66.
Gene Symbol CR2
Official Gene Full Name Complement receptor type 2
NCBI Gene Id 1380
Protein Name Complement receptor type 2
Swissprot Id P20023
Protein Accession # NP_001006659.1; NP_001868.2
Nucleotide Accession # NM_001006658.2; NM_001877.4
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express CR2.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express CR2.
  1. What is the species homology for "CR2 Antibody (OAEE00727)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Porcine, Bovine, Dog ".

  2. How long will it take to receive "CR2 Antibody (OAEE00727)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "CR2 Antibody (OAEE00727)" provided in?

    This item is provided in "".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CR2 Antibody (OAEE00727)"?

    This target may also be called "" in publications.

  5. What is the shipping cost for "CR2 Antibody (OAEE00727)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CR2 Antibody (OAEE00727)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CR2 Antibody (OAEE00727)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CR2 Antibody (OAEE00727)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "CR2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CR2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CR2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CR2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CR2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CR2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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