CHST5 Antibody - C-terminal region (OAAB14487)

Catalog No: OAAB14487

Size:400ul

CHST5 Antibody (C-term) (Cat. # OAAB14487) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the CHST5 antibody detected the CHST5 protein (arrow).

Product Info

• Predicted Species Reactivity: Human
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB
• Additional Information: Precautions: CHST5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues and O-linked sugars of mucin-type acceptors. Acts on the non-reducing terminal GlcNAc of short carbohydrate substrates However, it does not transfer sulfate to longer carbohydrate substrates that have poly-N-acetyllactosamine structures. Has no activity toward keratan. Not involved in generating HEV-expressed ligands for SELL. Its substrate specificity may be influenced by its subcellular location
  Cellular Location: Golgi apparatus membrane; Single-pass type II membrane protein (Probable). Note=Golgi membrane, early secretory pathway
  Tissue Location: Predominantly expressed in small and large intestines and colon. Weakly expressed in lymphocytes. Not expressed in other tissues. Down-regulated in colonic adenocarcinomas
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This CHST5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-302 amino acids from the C-terminal region of human CHST5.
• Predicted Homology Based on Immunogen Sequence: Human
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Application Info: WB: 1:1000

Target Info

• Gene Symbol: CHST5
• Alias Symbols: gn6st-3, hIGn6ST, I-GlcNAc6ST, glcNAc6ST-3, I-GlcNAc-6-ST
• NCBI Gene Id: 23563
• Protein Name: Carbohydrate sulfotransferase 5
• Description of Target: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: Q9GZS9
• Protein Accession #: NP_078809.2
• Molecular Weight: 46161 Da