CHPF Antibody (OAAF03494)

Catalog No: OAAF03494

Size:100 ug

Western blot analysis of extracts from LOVO/K562 cells, using CHSY2 Antibody. The lane on the right is treated with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue, using CHSY2 Antibody. The picture on the right is treated with the synthesized peptide.

Immunofluorescence analysis of MCF7 cells, using CHSY2 Antibody. The picture on the right is treated with the synthesized peptide.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid
• Clonality: Polyclonal
• Host: Rabbit
• Application: Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
• Reconstitution and Storage: -20°C
• Immunogen: The antiserum was produced against synthesized peptide derived from human CHSY2.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Specificity: CHSS2 antibody detects endogenous levels of total CHSS2 protein.
• Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Dilution: The optimal working dilution should be determined by the end user.
• Reference: Kitagawa H., J. Biol. Chem. 278:23666-23671(2003).
  Yada T., J. Biol. Chem. 278:30235-30247(2003).
  Clark H.F., Genome Res. 13:2265-2270(2003)

Target Info

• Gene Symbol: CHPF
• Gene Full Name: chondroitin polymerizing factor
• Alias Symbols: chondroitin glucuronyltransferase 2;chondroitin sulfate synthase 2;Chondroitin-polymerizing factor;CHSY2;CSS2;glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II;N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II;N-acetylgalactosaminyltransferase 2.
• NCBI Gene Id: 79586
• Protein Name: Chondroitin sulfate synthase 2
• Description of Target: Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Isoform 2 may facilitate PRKN transport into the mitochondria. In collaboration with PRKN, isoform 2 may enhance cell viability and protect cells from oxidative stress.
• Uniprot ID: Q8IZ52
• Protein Accession #: NP_001182660.1
• Molecular Weight: 85 kDa