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- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for anti-CDH1 (OAAJ01730) antibody |
|---|
| Predicted Species Reactivity | Human, Mouse, Rat |
|---|---|
| Product Format | Liquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | WB, IHC, IF, ICC |
| Reconstitution and Storage | Store at -20C. Stable for 12 months from date of receipt. |
| Immunogen | A synthesized peptide derived from human E-cadherin |
| Purification | Affinity-chromatography |
| Concentration | 1 mg/ml |
| Specificity | E-cadherin antibody detects endogenous levels of total E-cadherin |
| Application Info | WB: 1:500~1:3000 IHC: 1:50~1:200 IF/ICC: 1:100~1:500 |
| Gene Symbol | CDH1 |
|---|---|
| Gene Full Name | cadherin 1, type 1 |
| Alias Symbols | UVO, CDHE, ECAD, LCAM, Arc-1, BCDS1, CD324 |
| NCBI Gene Id | 999 |
| Description of Target | CDH1 a single-pass type I membrane protein, and calcium dependent cell adhesion proteins. It is a ligand for integrin alpha-E/beta-7, and it colocalizes with DLG7 at sites of cell-cell contact in intestinal epithelial cells. Anchored to actin microfilaments through association with alpha-, beta- and gamma-catenin. Sequential proteolysis induced by apoptosis or calcium influx, results in translocation from sites of cell-cell contact to the cytoplasm. Involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Defects in CDH1 are involved in dysfunction of the cell-cell adhesion system, triggering cancer invasion (gastric, breast, ovary, endometrium and thyroid) and metastasis. |
| Uniprot ID | P12830 |
| Molecular Weight | 120 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "CDH1 Antibody (OAAJ01730)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".
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How long will it take to receive "CDH1 Antibody (OAAJ01730)"?
This item is available "Domestic: within 2-3 week delivery | International: 2-3 weeks".
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What buffer format is "CDH1 Antibody (OAAJ01730)" provided in?
This item is provided in "Liquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "CDH1 Antibody (OAAJ01730)"?
This target may also be called "UVO, CDHE, ECAD, LCAM, Arc-1, BCDS1, CD324" in publications.
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What is the shipping cost for "CDH1 Antibody (OAAJ01730)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "CDH1 Antibody (OAAJ01730)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "CDH1 Antibody (OAAJ01730)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "120 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "CDH1 Antibody (OAAJ01730)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "CDH1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "CDH1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "CDH1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "CDH1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "CDH1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "CDH1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
