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CCT4 antibody - C-terminal region (ARP34271_P050)

100 ul
$319.00
In Stock

Conjugation Options

ARP34271_P050-FITC Conjugated

ARP34271_P050-HRP Conjugated

ARP34271_P050-Biotin Conjugated

Gene Symbol:
CCT4
NCBI Gene Id:
10575
Official Gene Full Name:
Chaperonin containing TCP1, subunit 4 (delta)
Protein Name:
T-complex protein 1 subunit delta
Swissprot Id:
Q53QP9
Protein Accession #:
NP_006421
Nucleotide Accession #:
NM_006430
Alias Symbols:
SRB, Cctd, CCT-DELTA
Replacement Item:
This antibody may replace item sc-137092 from Santa Cruz Biotechnology.
Description of Target:
The CCT (chaperonin containing TCP-1) complex functions as a molecular chaperone in the eukaryotic cytosol. CCT4 interacts with human cyclin E which has been implicated in positive control of the G1/S phase transition.
Protein Size (# AA):
539
Molecular Weight:
58kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express CCT4.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express CCT4.
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human CCT4
Species Reactivity:
Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Predicted Homology Based on Immunogen Sequence:
Cow: 93%; Dog: 93%; Goat: 79%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%; Yeast: 100%; Zebrafish: 93%
Complete computational species homology data:
Anti-CCT4 (ARP34271_P050)
Peptide Sequence:
Synthetic peptide located within the following region: AFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTAGINVRKGGISN
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
HUWE1; TP53; FUS; CDC20; NEDD1; TUBG1; LGALS3BP; UBC; STAU1; MDM2; RFWD2; VRK2; PRPF40A; CCT7; USP9X; VARS; CCT3; CCT6A; FBXO6; UBD; FBXW4; CDK9; CDK5; CDK2; CD81; IGSF8; HDAC11; HDAC3; RPS6KA1; ILK; ICAM1; PAN2; VCAM1; PPP5C; PEX14; NOS2; US3; FAM86B2; C
Blocking Peptide:
For anti-CCT4 (ARP34271_P050) antibody is Catalog # AAP34271 (Previous Catalog # AAPP05621)
Datasheets/Manuals:
Printable datasheet for anti-CCT4 (ARP34271_P050) antibody
Sample Type Confirmation:

CCT4 is supported by BioGPS gene expression data to be expressed in HEK293, HEK293T, HepG2

Subunit:
delta
Target Reference:
Parissi,V., et al., (2001) J. Virol. 75 (23), 11344-11353
Publications:

Laux, A. et al. Localization of endogenous morphine-like compounds in the mouse spinal cord. J. Comp. Neurol. 520, 1547-61 (2012). IHC, WB, Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish 22133715

Tarkar, A. et al. DYX1C1 is required for axonemal dynein assembly and ciliary motility. Nat. Genet. 45, 995-1003 (2013). IHC, WB, Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish 23872636

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