ADCY5 Antibody - C-terminal region (OASG00081)

Catalog No: OASG00081

Size:100 uL

Western Blot using COLO205

Western Blot using HuvEc, MCF7, PC-12

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC, IF
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from the C-terminal region of human A Cyclase V/VI. Location: 900-980aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: A Cyclase V/VI Polyclonal Antibody detects endogenous levels of A Cyclase V/VI protein.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000;

Target Info

• Gene Symbol: ADCY5, ADCY6
• Gene Full Name: adenylate cyclase 5
• Alias Symbols: AC5, FDFM
• NCBI Gene Id: 111; 112; 224129; 11512; 64532
• Description of Target: This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene.
• Uniprot ID: O95622, O43306, P84309, Q01341, Q04400, Q03343
• Molecular Weight: 138 kDa