Anti-Mcl-1 Antibody (OAED00048)

Catalog No: OAED00048

Size:50 ug

Western blot analysis of Mcl-1, pAb: Lane 1: MW marker; Lane 2: HeLa; Lane 3: 3T3; Lane 4: PC-12; Lane 5: MDCK; Lane 6: RK-13.

Immunohistochemistry analysis of human breast cancer tissue with Mcl-1 pAb.

Immunofluorescent analysis (confocal) staining of HeLa cells using Mcl-1 pAb (green); nuclei are stained in blue pseudocolor using DRAQ5.

Product Info

• Predicted Species Reactivity: Dog|Guinea Pig|Human|Monkey|Porcine|Rabbit
• Clonality: Polyclonal
• Host: Rabbit
• Application: Immunofluorescence|Western blot
• Reconstitution and Storage: Long Term Storage : -20C
  
• Immunogen: Synthetic peptide corresponding to a portion of human Mcl-1.
• Specificity: Recognizes human, dog, guinea pig, monkey, pig and rabbit Mcl-1. Detects a band of ~42/43kDa by Western blot.
• Formulation: Liquid. In PBS containing 0.09% sodium azide.
• Purity: Peptide affinity purified.
  
• Application Info: Immunofluorescence
  Immunohistochemistry (paraffin sections) (1:50)
  Western Blot (0.2μg/ml, ECL)
  Optimal conditions must be determined individually for each application

Target Info

• Gene Symbol: MCL1
• Gene Full Name: MCL1 apoptosis regulator, BCL2 family member
• Alias Symbols: BCL2 family apoptosis regulator;bcl2-L-3;BCL2L3;bcl-2-like protein 3;bcl-2-related protein EAT/mcl1;EAT;induced myeloid leukemia cell differentiation protein Mcl-1;Mcl-1;MCL1, BCL2 family apoptosis regulator;mcl1/EAT;MCL1-ES;MCL1L;MCL1S;myeloid cell leukemia 1;myeloid cell leukemia ES;myeloid cell leukemia sequence 1 (BCL2-related);TM.
• NCBI Gene Id: 4170
• Protein Name: Induced myeloid leukemia cell differentiation protein Mcl-1
• Description of Target: Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
• Uniprot ID: Q07820