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- $55: Antibody & Protein in US
- $55 + $25/Kit in US
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| Datasheets/Manuals | Printable datasheet for anti-MCL1 (OAEC04260) antibody |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Purified antibody in PBS containing 0.03% sodium azide |
| Clonality | Monoclonal |
| Clone | 8C6,8C6D4B1 |
| Isotype | IgG1 |
| Host | Mouse |
| Reconstitution and Storage | Store at 4C, for long term storage, store at -20C. |
| Immunogen | Purified recombinant fragment of human MCL-1 expressed in EColi |
| Concentration | 1 mg/ml |
| Application Info | WB: 1/500 - 1/2000 IHC: 1/200 - 1/1000 IF: 1/200 - 1/1000 ELISA: 1/10000 Figure 2 Immunohistochemical analysis of paraffin-embedded humanlym phnode tissues using MCL1 mouse mAb with DAB staining |
| Gene Symbol | MCL1 |
|---|---|
| Gene Full Name | myeloid cell leukemia 1 |
| Alias Symbols | TM, EAT, MCL1L, MCL1S, Mcl-1, BCL2L3, MCL1-ES, bcl2-L-3, mcl1/EAT |
| NCBI Gene Id | 4170 |
| Description of Target | Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene that increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lym phocytes undergoing apoptosis following treatm ent with apoptotic stimuli such as TGF-alpha 1 and forskolin. Expres sion of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSm yc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related protein, Bax, and prolongs cell viability after treatm ent with different apoptotic reagents.This monoclonal antibody detected a 37kd MCL1 in BCBL-1 cell lys ate. |
| Uniprot ID | Q07820 |
| Molecular Weight | 37 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "MCL1 Antibody (OAEC04260)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "MCL1 Antibody (OAEC04260)"?
This item is available "Domestic: within 2-3 weeks delivery | International: 2-3 weeks".
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What buffer format is "MCL1 Antibody (OAEC04260)" provided in?
This item is provided in "Purified antibody in PBS containing 0.03% sodium azide".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "MCL1 Antibody (OAEC04260)"?
This target may also be called "TM, EAT, MCL1L, MCL1S, Mcl-1, BCL2L3, MCL1-ES, bcl2-L-3, mcl1/EAT" in publications.
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What is the shipping cost for "MCL1 Antibody (OAEC04260)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "MCL1 Antibody (OAEC04260)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "MCL1 Antibody (OAEC04260)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "37 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "MCL1 Antibody (OAEC04260)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "MCL1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "MCL1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "MCL1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "MCL1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "MCL1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "MCL1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
