MCL1 Antibody (Phospho-Ser159) (OASG04407)

Catalog No: OASG04407

Size:100 uL

Western Blot using K562

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: IF
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human Mcl-1 around the phosphorylation site of S159. Location: 100-180aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Phospho-Ser159
• Specificity: Phospho-Mcl-1 (S159) Polyclonal Antibody detects endogenous levels of Mcl-1 protein only when phosphorylated at S159.
• Application Info: IF 1:200-1:1000; ELISA 1:10000;

Target Info

• Gene Symbol: MCL1
• Gene Full Name: myeloid cell leukemia 1
• Alias Symbols: TM, EAT, MCL1L, MCL1S, Mcl-1, BCL2L3, MCL1-ES, bcl2-L-3, mcl1/EAT
• NCBI Gene Id: 4170; 17210;
• Description of Target: This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
• Uniprot ID: Q07820, P97287
• Molecular Weight: 39 kDa