TAF1 Recombinant Protein (OPCD07267)

Catalog No: OPCD07267

TAF1 Recombinant Protein (OPCD07267) using SDS-PAGE

TAF1 Recombinant Protein (OPCD07267) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Thr1379-Pro1636
  Subcellular Location: Nucleus.
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: TAF1
• Gene Full Name: TATA-box binding protein associated factor 1
• Alias Symbols: BA2R;CCG1;CCGS;cell cycle gene 1 protein;cell cycle, G1 phase defect;complementation of cell cycle block, G1-to-S;DYT3;DYT3/TAF1;KAT4;MRXS33;NSCL2;N-TAF1;OF;P250;TAF(II)250;TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa;TAF2A;TAFII250;TAFII-250;TBP-associated factor 250 kDa;transcription factor TFIID p250 polypeptide;Transcription initiation factor TFIID 250 kDa subunit;transcription initiation factor TFIID subunit 1;XDP.
• NCBI Gene Id: 6872
• Protein Name: Transcription initiation factor TFIID subunit 1
• Description of Target: Largest component and core scaffold of the TFIID basal transcription factor complex (PubMed:25412659, PubMed:27007846). Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity (PubMed:25412659). Essential for progression of the G1 phase of the cell cycle (PubMed:11278496, PubMed:15053879, PubMed:2038334, PubMed:8450888, PubMed:8625415, PubMed:9660973, PubMed:9858607). Exhibits histone acetyltransferase activity towards histones H3 and H4 (PubMed:15870300).
• Uniprot ID: P21675
• Protein Accession #: NP_001273003.1
• Nucleotide Accession #: NM_001286074.1
• Protein Size (# AA): Thr1379~Pro1636
• Molecular Weight: 34kDa