- Description of Target:
- This protein is beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
- Gene Symbol:
- ADRB2
- Official Gene Full Name:
- Adrenergic, beta-2-, receptor, surface
- Alias Symbols:
- ADRB2R; ADRBR; B2AR; BAR; BETA2AR
- Tissue Tool:
- Find tissues and cell lines supported to express ADRB2.
- Protein Accession# :
- NP_000015
- Nucleotide Accession#:
- NM_000024
- Swissprot Id:
- P07550
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Protein Size (# AA):
- 413
- Molecular Weight:
- 46kDa
- Application:
- WB
- Partner Proteins:
- HHV4gp086, APEX1, AURKA, GORASP2, ITGB1, KSR1, MIF, NME1, NME3, NME4, POLR1C, PRUNE, RORA, RORB, RRAD, SET, TERF1, TIAM1, WDYHV1, AURKA, GORASP2, ITGB1, NME1, NME3, NME4, POLR1C, PRUNE, RAC1, RORA, RORB, RRAD, SET, TERF1, TIAM1, USP18, WDYHV1
- Immunogen:
- The immunogen for anti-ADRB2 antibody: synthetic peptide directed towards the middle region of human ADRB2
- Product Format:
- Lyophilized powder
- Purification:
- Affinity Purified
- Complete computational species homology data:
- ADRB2 antibody - middle region (AVARP00006_P050)
- Predicted Homology Based on Immunogen Sequence:
- Human: 100%
- Datasheets / Downloads:
- Printable datasheet for
anti-ADRB2 antibody
- AVARP00006_P050 - Peptide Sequence:
- Synthetic peptide located within the following region: TGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTN
- Blocking Peptide:
- For anti-ADRB2 antibody is Catalog # AAP30422 (Previous Catalog # AAPP01005)
- Key Reference:
- Penco,S., (er) BMC Bioinformatics 9 (1), 254 (2008) In press
- Reconstitution and Storage:
- Add 50 μl of distilled water. Final anti-ADRB2 antibody concentration is 1 mg/ml in PBS buffer. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Product Protocols: ADRB2 antibody tested with Human Ovcar-3 Cells (AVARP00006_P050)
Aviva Systems Biology is the original manufacturer of this ADRB2 antibody (AVARP00006_P050)
Click here to view the ADRB2 antibody Western Blot Protocol
Product Datasheet Link: ADRB2 antibody (AVARP00006_P050)
WB Suggested Anti-ADRB2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: OVCAR-3
Western Blot image: 
Description of Target: This protein is beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Questions pertaining to this data can be directed to techsupport@avivasysbio.com
Aviva Systems Biology’s ADRB2 antibody (AVARP00006_P050) has been tested using other cell lysates and tissues. To obtain more data about this antibody please email us at info@avivasysbio.com.
To order by phone call us at (888) 880-0001, fax us at (858) 552-6975 or send an email to info@avivasysbio.com. Aviva manufactures this antibody so we can offer the best price. Please contact us to request pricing information.
All of Aviva’s products are guaranteed for the applications and experimental sample types mentioned in the datasheet below. Are you curious if this product will work for you? Please contact us at techsupport@avivasysbio.com
- Protocol:
- Tips Information:
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