ADRB2 Antibody - middle region (AVARP00006_P050)

Data Sheet
 
Product Number AVARP00006_P050
Product Page www.avivasysbio.com/adrb2-antibody-middle-region-avarp00006-p050.html
Name ADRB2 Antibody - middle region (AVARP00006_P050)
Protein Size (# AA) 413 amino acids
Molecular Weight 46kDa
NCBI Gene Id 154
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name Adrenergic, beta-2-, receptor, surface
Alias Symbols BAR, B2AR, ADRBR, ADRB2R, BETA2AR
Peptide Sequence Synthetic peptide located within the following region: TGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTN
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Penco,S., (er) BMC Bioinformatics 9 (1), 254 (2008) In press
Description of Target This protein is beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Protein Interactions ARRDC3; REL; TSHR; TSG101; STAT4; STAT3; SNCG; RGS10; RGS2; RAN; RAB27A; RAB3A; CNN1; CD81; CD68; CD9; CD4; CCKBR; CEACAM1; ARRB2; ARHGDIA; ARHGAP5; HDAC6; GPR56; VAPA; RGS9; RGS11; RGS20; RGS5; VEGFB; VDAC2; VDAC1; KCTD13; ARRDC1; RGS8; SLC52A2; WNK1; RA
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-ADRB2 (AVARP00006_P050) antibody
Blocking Peptide For anti-ADRB2 (AVARP00006_P050) antibody is Catalog # AAP30422 (Previous Catalog # AAPP01005)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human ADRB2
Uniprot ID P07550
Protein Name Beta-2 adrenergic receptor
Protein Accession # NP_000015
Purification Affinity Purified
Nucleotide Accession # NM_000024
Tested Species Reactivity Human
Gene Symbol ADRB2
Predicted Species Reactivity Human
Application WB
Predicted Homology Based on Immunogen Sequence Human: 100%
Image 1
Human OVCAR-3
WB Suggested Anti-ADRB2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: OVCAR-3 cell lysate
Image 2
Hum. Fetal Lung
Hum. Fetal Lung
Image 3
Human Fetal Lung
Host: Rabbit
Target Name: ADRB2
Sample Type: Human Fetal Lung
Antibody Dilution: 1.0ug/ml
 

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