| Sku |
AAP30422 |
| Old sku |
AAPP01005 |
| Price |
$99.00 |
| Name |
ADRB2 Peptide - middle region (AAP30422) |
| Purchase info |
To purchase this peptide:
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|
| Size |
100 ug |
| Gene |
ADRB2 |
| Alias symbols |
ADRB2R, ADRBR, B2AR, BAR, BETA2AR |
| Gene id |
154 |
| Description of target |
This protein is beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Swissprot id |
P07550 |
| Protein accession num |
NP_000015 |
| Nucleotide accession num |
NM_000024 |
| Protein size |
413 amino acids |
| Molecular weight |
46kDa |
| Application |
WB |
| Partner proteins |
EIF2B1,SLC9A3R1,SLC9A3R2,ADRB3,AKAP12,AKAP5,ARR3,ARRB1,CSK,EIF2B1,GNA11,GNA14,GNA15,GPRASP1,GRB2,GRK5,GRK6,HTR4,IL1B,INSR,KCNJ6,KCNJ9,NOS1,OPRD1,PRKCD,SLC9A3R1,SLC9A3R2,SRC,ADRB2,ADRBK1,AKAP12,Arrb2,EIF2B1,GRB2,GRK6,KCNJ3,KCNJ5,OPRD1,PPP3CA,SLC9A3R1,SLC9A3R2,SRC,UBC |
| Quality control |
The peptide is characterized by mass spectroscopy |
| Key reference |
Penco,S., (er) BMC Bioinformatics 9 (1), 254 (2008) In press |
| Description |
This is a synthetic peptide designed for use in combination with anti-ADRB2 antibody (Catalog #: AVARP00006_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details. |
| Product format |
Lyophilized powder |
| Reconstitution and storage |
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. |
| Lead time |
Domestic: within 24 hours delivery International: 3-5 business days |
| Protocol |
|
| Tips |
See our General FAQ page. |
| Availability |
In Stock |
