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Datasheets/Manuals | Printable datasheet for anti-NKX2-5 (OAAB19069) antibody |
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Predicted Species Reactivity | Mouse, Rat |
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Product Format | Liquid. PBS with 0.09% (W/V) sodium azide. |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Application | WB |
:: | Cellular Location: Nucleus. Tissue Location: Predominantly in the adult and embryonic heart, and to a lesser extent in lingual muscle, spleen and stomach. |
Reconstitution and Storage | Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
Immunogen | This mouse Nkx2-5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 192-235 amino acids from the Central region of mouse Nkx2-5. |
Purification | This antibody is purified through a protein A column, followed by peptide affinity purification. |
Predicted Homology Based on Immunogen Sequence | Rat |
Concentration | 0.5 mg/ml |
Intended Use | Mouse Nkx2-5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Application Info | WB: 1:1000 |
Reference | Lints T.J.,et al.Development 119:419-431(1993). Lints T.J.,et al.Development 119:969-969(1993). Searcy R.D.,et al.Development 125:4461-4470(1998). Komuro I.,et al.Proc. Natl. Acad. Sci. U.S.A. 90:8145-8149(1993). Kim Y.H.,et al.J. Biol. Chem. 273:25875-25879(1998). |
Gene Symbol | NKX2-5 |
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Alias Symbols | Cs, ti, Csx, Nkx2., Nkx-2., Nkx2.5, tinman, Nkx-2.5 |
NCBI Gene Id | 18091 |
Description of Target | Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4. It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B. Together with PBX1, it is required for spleen development through a mechanism that involves CDKN2B repression. |
Uniprot ID | P42582; O35767 |
Molecular Weight | 34 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Nkx2-5 Antibody - middle region (OAAB19069)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Mouse, Rat".
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How long will it take to receive "Nkx2-5 Antibody - middle region (OAAB19069)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
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What buffer format is "Nkx2-5 Antibody - middle region (OAAB19069)" provided in?
This item is provided in "Liquid. PBS with 0.09% (W/V) sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Nkx2-5 Antibody - middle region (OAAB19069)"?
This target may also be called "Cs, ti, Csx, Nkx2., Nkx-2., Nkx2.5, tinman, Nkx-2.5" in publications.
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What is the shipping cost for "Nkx2-5 Antibody - middle region (OAAB19069)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Nkx2-5 Antibody - middle region (OAAB19069)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Nkx2-5 Antibody - middle region (OAAB19069)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "34 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Nkx2-5 Antibody - middle region (OAAB19069)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "NKX2-5"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "NKX2-5"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "NKX2-5"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "NKX2-5"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "NKX2-5"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "NKX2-5"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.