- Description of Target:
- TSHR is receptor for thyrothropin. It plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. It also acts as a receptor for thyrostimulin (GPA2+GPB5).
- Gene Symbol:
- Official Gene Full Name:
- Thyroid stimulating hormone receptor
- NCBI Gene Id:
- Alias Symbols:
- LGR3; MGC75129; hTSHR-I; CHNG1
- Tissue Tool:
- Find tissues and cell lines supported to express TSHR.
- Protein Accession# :
- Nucleotide Accession#:
- Swissprot Id:
- Protein Name:
- Thyrotropin receptor
- Protein Size (# AA):
- Molecular Weight:
- The immunogen for anti-TSHR antibody: synthetic peptide directed towards the C terminal of human TSHR
- Product Format:
- Lyophilized powder
- Affinity Purified
- Complete computational species homology data:
- TSHR antibody - C-terminal region (ARP41871_P050)
- Predicted Homology Based on Immunogen Sequence:
- Human: 100%; Dog: 92%; Horse: 92%; Rat: 92%; Guinea pig: 85%; Mouse: 85%; Pig: 85%; Rabbit: 85%; Bovine: 83%; Sheep: 78%
- Species Reactivity:
- Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep
- Datasheets / Downloads:
- Printable datasheet for
anti-TSHR antibody- ARP41871_P050
- Peptide Sequence:
- Synthetic peptide located within the following region: KLDAVYLNKNKYLTVIDKDAFGGVYSGPSLLLPLGRKSLSFETQKAPRSS
- Blocking Peptide:
- For anti-TSHR antibody is Catalog # AAP41871 (Previous Catalog # AAPP24408)
- Key Reference:
- Claus,M., (2005) Endocrinology 146 (12), 5197-5203
- Reconstitution and Storage:
- Add 50 ul of distilled water. Final anti-TSHR antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Aviva Systems Biology is the original manufacturer of this TSHR antibody (ARP41871_P050)
Click here to view the TSHR antibody Western Blot Protocol
Product Datasheet Link: TSHR antibody (ARP41871_P050)
WB Suggested Anti-TSHR Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat
Western Blot image:
Description of Target: TSHR is receptor for thyrothropin. It plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. It also acts as a receptor for thyrostimulin (GPA2+GPB5).
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Aviva Systems Biology’s TSHR antibody (ARP41871_P050) has been tested using other cell lysates and tissues. To obtain more data about this antibody please email us at firstname.lastname@example.org.
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