BCL2L11 Antibody - middle region (ARP78286_P050)

Catalog No: ARP78286_P050

Host: Rabbit
Target Name: BCL2L11
Sample Tissue: Human DLD1 Whole Cell
Antibody Dilution: 1.0ug/ml

Rabbit Anti-BCL2L11 Antibody
Catalog Number: ARP78286_P050
Formalin Fixed Paraffin Embedded Tissue: Human Lymph Node Tissue
Observed Staining: Cytoplasm
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BCL2L11
• Purification: Affinity purified
• Peptide Sequence: Synthetic peptide located within the following region: PAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASP
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-BCL2L11 (ARP78286_P050) antibody is Catalog # AAP78286

Target Info

• Gene Symbol: BCL2L11
• Gene Full Name: BCL2-like 11 (apoptosis facilitator)
• Alias Symbols: BAM, BIM, BOD
• NCBI Gene Id: 10018
• Protein Name: bcl-2-like protein 11
• Description of Target: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.
• Uniprot ID: O43521
• Protein Accession #: NP_001191035.1
• Nucleotide Accession #: NM_001204106.1
• Protein Size (# AA): 198
• Molecular Weight: 22 kDa