BCL2L11 Recombinant Protein (OPCD01605)

Catalog No: OPCD01605

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ala2-Arg120
  Subcellular Location: Mitochondrion.
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: BCL2L11
• Gene Full Name: BCL2 like 11
• Alias Symbols: BAM;bcl-2 interacting mediator of cell death;bcl-2 interacting protein Bim;Bcl2-interacting mediator of cell death;BCL2-like 11 (apoptosis facilitator);bcl-2-like protein 11;bcl-2-related ovarian death agonist;BIM;BOD.
• NCBI Gene Id: 10018
• Protein Name: Bcl-2-like protein 11
• Description of Target: Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.
• Uniprot ID: O43521
• Protein Accession #: NP_001191035.1
• Nucleotide Accession #: NM_001204106.1
• Protein Size (# AA): Ala2~Arg120
• Molecular Weight: 18kDa