TYMS Antibody (OAPA00338)

Catalog No: OAPA00338 (Formerly GWB-BSP871)

Size:5UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
• Clonality: Monoclonal
• Clone: PAT1S5AT.
• Isotype: Mouse IgG2b heavy chain and kappa light chain.
• Host: Mouse
• Application: WB
  Product Introduction: Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate as a cofactor which maintains the dTMP (thymidine-5-prime monophosphate) pool vital for DNA replication and repair. Thymidylate synthase plays an important role as a cancer chemotherapeutic agent. Thymidylate synthase is the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and several folate analogs.
  Product Description: Mouse Anti Human Thymidylate Synthetase
• Reconstitution and Storage: For periods up to 1 month store at 4C, for longer periods of time, store at -20C. Prevent freeze thaw cycles.
  Stability: 12 months at -20C. 1 month at 4C.
• Immunogen: The immunogen for anti-TYMS antibody: anti-human TYMS mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TYMS amino acids 1-313 purified from E. coli.
• Purity: TYMS antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
• Application Info: TYMS antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot and Immunofluorescence analysis is 1:500 ~ 1000. Recommended starting dilution is 1:500.

Target Info

• Gene Symbol: TYMS
• Alias Symbols: TS, TMS, HST422
• NCBI Gene Id: 7298
• Protein Name: Thymidylate synthase
• Description of Target: Mouse Anti Human Thymidylate Synthetase
• Uniprot ID: P04818