MARCO Antibody - C-terminal region (ARP41581_P050)

Catalog No: ARP41581_P050

Host: Rabbit
Target Name: MARCO
Sample Tissue: Human HCT116 Whole Cell
Antibody Dilution: 3ug/ml

WB Suggested Anti-MARCO Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: COLO205 cell lysateMARCO is supported by BioGPS gene expression data to be expressed in COLO205

Host: Rabbit
Target: MARCO
Positive control (+): Human lung (LU)
Negative control (-): Human brain (BR)
Antibody concentration: 1ug/ml

Host: Rabbit
Target Name: MARCO
Sample Tissue: Human A549 Whole Cell
Antibody Dilution: 0.5ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Horse, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MARCO
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Horse: 86%; Human: 100%; Mouse: 85%; Rat: 85%; Zebrafish: 92%
• Peptide Sequence: Synthetic peptide located within the following region: GPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERGE
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-MARCO (ARP41581_P050) antibody is Catalog # AAP41581 (Previous Catalog # AAPP24266)
• Sample Type Confirmation:

  MARCO is supported by BioGPS gene expression data to be expressed in COLO205

• Enhanced Validation:

  WB	Y
  SPR
  YCHAROS

Target Info

• Gene Symbol: MARCO
• Gene Full Name: Macrophage receptor with collagenous structure
• Alias Symbols: SR-A6, SCARA2
• NCBI Gene Id: 8685
• Protein Name: Macrophage receptor MARCO
• Description of Target: The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.
• Uniprot ID: Q9UEW3
• Protein Accession #: NP_006761
• Nucleotide Accession #: NM_006770
• Protein Size (# AA): 520
• Molecular Weight: 53 kDa
• Protein Interactions: SCGB3A2; SCGB3A1;