EPS15 Antibody - C-terminal region (ARP54601_P050)

Catalog No: ARP54601_P050

WB Suggested Anti-EPS15 Antibody Titration: 0.2-1 ug/ml
Positive Control: 721_B cell lysateEPS15 is supported by BioGPS gene expression data to be expressed in 721_B

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human EPS15
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 93%; Guinea Pig: 79%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: LDSPDPFKLNDPFQPFPGNDSPKEKDPEIFCDPFTSATTTTNKEADPSNF
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-EPS15 (ARP54601_P050) antibody is Catalog # AAP54601 (Previous Catalog # AAPP31385)
• Sample Type Confirmation:

  EPS15 is supported by BioGPS gene expression data to be expressed in 721_B

• Reference: Niehof,M. (2008) Gastroenterology 134 (4), 1191-1202

Target Info

• Gene Symbol: EPS15
• Gene Full Name: Epidermal growth factor receptor pathway substrate 15
• Alias Symbols: AF1P, AF-1P, MLLT5
• NCBI Gene Id: 2060
• Protein Name: Epidermal growth factor receptor substrate 15
• Description of Target: EPS15 is a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias.This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Uniprot ID: P42566
• Protein Accession #: NP_001972
• Nucleotide Accession #: NM_001981
• Protein Size (# AA): 896
• Molecular Weight: 99kDa
• Protein Interactions: TRIM63; UBC; GJA1; EPHA2; CORO7; RNF11; RABL6; OPTN; LAPTM5; VCAM1; ITGA4; FN1; Fcho2; Dab2; STON2; EPN1; AGFG1; EPS15; CRKL; CRK; AP2S1; AP2M1; AP2B1; AP1B1; AP2A2; AP2A1; ACTB; ABL1; NECAP1; SPG20; VPRBP; KRT75; IQGAP1; KRT36; KRT37; KRT38; CCT3; TRAF2;