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Datasheets/Manuals | Printable datasheet for anti-MME (ARP63365_P050) antibody |
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Tested Species Reactivity | Human, Mouse |
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Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit |
Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Clonality | Polyclonal |
Host | Rabbit |
Application | WB |
Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 100% |
Peptide Sequence | Synthetic peptide located within the following region: EYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW |
Concentration | 0.5 mg/ml |
Blocking Peptide | For anti-MME (ARP63365_P050) antibody is Catalog # AAP63365 |
Gene Symbol | MME |
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Gene Full Name | Membrane metallo-endopeptidase |
Alias Symbols | NEP, SFE, CD10, CALLA, CMT2T, SCA43 |
NCBI Gene Id | 4311 |
Protein Name | Neprilysin |
Description of Target | This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. |
Uniprot ID | P08473 |
Protein Accession # | NP_009218 |
Nucleotide Accession # | NM_007287 |
Protein Size (# AA) | 750 |
Molecular Weight | 83kDa |
Protein Interactions | MME; NPPA; AGT; HDAC8; UBC; NDRG1; FAM83F; RGPD6; POTEI; TUBB8; UBAC2; KBTBD3; MTDH; ITFG3; ARMC10; FAHD1; CDK5RAP3; MRPL44; NUCKS1; MRPS25; LAMTOR1; DNAJB12; SDF4; METTL7A; NNT; CPSF6; PDIA5; RUVBL2; TM9SF1; MRVI1; CLEC4M; ZMPSTE24; RBM39; ATP5J2; SLC9A3 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "MME Antibody - C-terminal region (ARP63365_P050)"?
The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit".
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How long will it take to receive "MME Antibody - C-terminal region (ARP63365_P050)"?
This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".
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What buffer format is "MME Antibody - C-terminal region (ARP63365_P050)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "MME Antibody - C-terminal region (ARP63365_P050)"?
This target may also be called "NEP, SFE, CD10, CALLA, CMT2T, SCA43" in publications.
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What is the shipping cost for "MME Antibody - C-terminal region (ARP63365_P050)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "MME Antibody - C-terminal region (ARP63365_P050)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "MME Antibody - C-terminal region (ARP63365_P050)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "83kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "MME Antibody - C-terminal region (ARP63365_P050)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "MME"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "MME"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "MME"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "MME"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "MME"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "MME"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.