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- $55: Antibody & Protein in US
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| Datasheets/Manuals | Printable datasheet for PTGS2 Antibody (OAAF01763) |
|---|
| Predicted Species Reactivity | Human|Mouse|Rat |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot |
| Reconstitution and Storage | -20°C |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Cox2. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Specificity | Cox2 antibody detects endogenous levels of total Cox2 protein. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Dilution | The optimal working dilution should be determined by the end user. |
| Application Info | WB: 1:500~1:1000; IHC: 1:50~1:100; IF: 1:100~1:500; ELISA: 1:20000 |
| Reference | Nathalie Bonnefoy, Mol. Cell. Biol., Apr 2001; 21: 2359 - 2372. Keith P. Choe, J. Exp. Biol., May 2006; 209: 1696 - 1708 D. Shelley Lupold, PNAS, Sep 1999; 96: 11670. Axel J. Baumgarten, AACR Meeting Abstracts, Mar 2004; 2004: 1078. |
| Gene Symbol | PTGS2 |
|---|---|
| Gene Full Name | prostaglandin-endoperoxide synthase 2 |
| Alias Symbols | COX2;COX-2;cyclooxygenase 2;cyclooxygenase 2b;Cyclooxygenase-2;GRIPGHS;hCox-2;PGG/HS;PGH synthase 2;PGHS-2;PHS II;PHS-2;prostaglandin G/H synthase 2;prostaglandin H2 synthase 2;Prostaglandin-endoperoxide synthase 2;prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase). |
| NCBI Gene Id | 5743 |
| Protein Name | Prostaglandin G/H synthase 2 |
| Description of Target | Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis (PubMed:26859324, PubMed:27226593). Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis. |
| Uniprot ID | P35354 |
| Protein Accession # | NP_000954.1 |
| Molecular Weight | 68 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "PTGS2 Antibody (OAAF01763)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".
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How long will it take to receive "PTGS2 Antibody (OAAF01763)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "PTGS2 Antibody (OAAF01763)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "PTGS2 Antibody (OAAF01763)"?
This target may also be called "COX2;COX-2;cyclooxygenase 2;cyclooxygenase 2b;Cyclooxygenase-2;GRIPGHS;hCox-2;PGG/HS;PGH synthase 2;PGHS-2;PHS II;PHS-2;prostaglandin G/H synthase 2;prostaglandin H2 synthase 2;Prostaglandin-endoperoxide synthase 2;prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)." in publications.
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What is the shipping cost for "PTGS2 Antibody (OAAF01763)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "PTGS2 Antibody (OAAF01763)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "PTGS2 Antibody (OAAF01763)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "68 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "PTGS2 Antibody (OAAF01763)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "PTGS2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "PTGS2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "PTGS2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "PTGS2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "PTGS2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "PTGS2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
