PDZD2 Antibody (OAGA00624)

Catalog No: OAGA00624

Size:100 ul

Sample (30 ug of whole cell lysate)
A: A549 5% SDS PAGE
OAGA00624 diluted at 1:1000

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB
• Additional Information: Background: Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq]
  Positive Controls: A549
  Cellular Localization: Nucleus (By similarity), Cytoplasm, Endoplasmic reticulum, Processed PDZ domain-containing protein 2: Secreted
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Synthetic peptide corresponding to a region within amino acids 1 and 44 of PDZK3 (Uniprot ID#O15018)
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 1 mg/ml
• Application Info: Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Target Info

• Gene Symbol: PDZD2
• Gene Full Name: PDZ domain-containing protein 2
• Alias Symbols: AIPC, PIN1, PAPIN, PDZK3
• NCBI Gene Id: 23037
• Protein Name: PDZ domain-containing protein 2
• Uniprot ID: O15018
• Protein Accession #: NP_835260.2
• Molecular Weight: 302 kDa