Interleukin-2 (Western Blot Control) Protein (OPRB00166)

Datasheets/Manuals	Printable datasheet for Interleukin-2 (Western Blot Control) Protein (OPRB00166)

Product Info
Product Format	Liquid. Supplied in 1x Laemmli Buffer (25mM Tris-HCl pH6.8, 50mM DTT, 1% (w/v) SDS, 0.1% (w/v) Bromophenol Blue, 2.5% Glycerol).
Application	Control\|Western blot
Purity	Single band on Western blot.
Reference	Fletcher, M. & Goldstein, A.L. (1987) Lymphokine Res. 6(1): 45- 57. Jelinek, D.F. et al., (1986) Eur. J. Immunol. 16(8): 925- 932.

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Protein interactions

Biological pathways

Name	# of Products
Anti-apoptosis	727
Cell adhesion	1115
Cell-cell signaling	763
Immune response	1416
Natural killer cell activation	93
Negative regulation of B cell apoptosis	25
Positive regulation of activated T cell proliferation	123
Positive regulation of B cell proliferation	254
Positive regulation of cell growth	178
Positive regulation of inflammatory response	172
Positive regulation of interleukin-17 production	72
Positive regulation of tissue remodeling	50
Positive regulation of tyrosine phosphorylation of Stat5 protein	127
T cell differentiation	128

Biological process

Name	# of Products
Activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway	31
Anti-apoptosis	239
Cell adhesion	446
Cell-cell signaling	235
Elevation of cytosolic calcium ion concentration	113
Immune response	404
Natural killer cell activation	18
Negative regulation of B cell apoptosis	7
Negative regulation of heart contraction	6
Negative regulation of inflammatory response	54
Negative regulation of lymphocyte proliferation	9
Negative regulation of protein phosphorylation	40
Positive regulation of activated T cell proliferation	45
Positive regulation of B cell proliferation	66
Positive regulation of cell growth	70
Positive regulation of cell proliferation	483
Positive regulation of immunoglobulin secretion	24
Positive regulation of inflammatory response	57
Positive regulation of interleukin-17 production	27
Positive regulation of isotype switching to IgG isotypes	27
Positive regulation of phosphorylation	34
Positive regulation of protein phosphorylation	125
Positive regulation of regulatory T cell differentiation	6
Positive regulation of tissue remodeling	6
Positive regulation of transcription from RNA polymerase II promoter	968
Positive regulation of tyrosine phosphorylation of Stat5 protein	37
Regulation of T cell homeostatic proliferation	8
T cell differentiation	39

Cellular components

Name	# of Products
Extracellular region	1573
Extracellular space	884

Protein function

Name	# of Products
Carbohydrate binding	111
Cytokine activity	1104
Glycosphingolipid binding	66
Growth factor activity	831
Interleukin-2 receptor binding	47
Kappa-type opioid receptor binding	35
Kinase activator activity	33

Diseases

Name	# of Products
Proto-oncogene	793

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