Anti-GLUT-1 Polyclonal Antibody (OAAI00167)

Catalog No: OAAI00167

Size:100UG

IHC: Human esophagus tissue stained with Anti- GLUT1 antibody, Cat#OAAI00167 at 1:50 for 10 min @ RT. Staining of formalin- fixed tissue requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid. This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Host: Rabbit
• Application: Enzyme-linked immunosorbent assay|Flow cytometry|Immunohistochemistry|Immunoprecipitation|Western blot
• Additional Information: Background: Glucose is fundamental to the metabolism of mammalian cells. Several glucose transporter protein (Glut) isoforms have been identified and shown to function in response to insulin and IGF-1 induced signaling. GLUT-1 is detectable in many human tissues including those of the colon, lung, stomach, esophagus, and breast.
  Positive Control: Breast Cancer Tissue
  Cellular Location: Membrane
• Reconstitution and Storage: The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
• Immunogen: A synthetic peptide derived from C-terminus of human Glut-1 Protein. This sequence is identical to human and rat.
• Purification: Affinity Purified
• Concentration: 100ug/200ul
• Specificity: SLC2A1
• Formulation: This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
• Application Info: WB: 0.1-1 ug/ml | ELISA: 0.01-0.1 ug/ml | IP: 2-5 ug/ml | IHC: 2-10 ug/ml | FC: Not tested
• Reference: Bonsi P, Cuomo D, De Persis C, Centonze D, Bernardi G, Calabresi P, Pisani A (2005). "Modulatory action of metabotropic glutamate receptor (mGluR) 5 on mGluR1 function in striatal cholinergic interneurons". Neuropharmacology 49 Suppl 1: 104–13.
  

Target Info

• Gene Symbol: SLC2A1
• Gene Full Name: solute carrier family 2 member 1
• Alias Symbols: choreoathetosis/spasticity, episodic (paroxysmal choreoathetosis/spasticity);CSE;DYT17;DYT18;DYT9;EIG12;glucose transporter type 1, erythrocyte/brain;GLUT;GLUT1;GLUT-1;GLUT1DS;hepG2 glucose transporter;HTLVR;human T-cell leukemia virus (I and II) receptor;PED;receptor for HTLV-1 and HTLV-2;SDCHCN;solute carrier family 2 (facilitated glucose transporter), member 1;solute carrier family 2, facilitated glucose transporter member 1.
• NCBI Gene Id: 6513
• Description of Target: Glucose is fundamental to the metabolism of mammalian cells. Several glucose transporter protein (Glut) isoforms have been identified and shown to function in response to insulin and IGF-1 induced signaling. GLUT-1 is detectable in many Human tissues including those of the colon, lung, stomach, esophagus, and breast.
  
• Uniprot ID: P11166
• Molecular Weight: 55