| Product Number |
ARP47601_P050 |
| Product Page |
www.avivasysbio.com/pa2g4-antibody-c-terminal-region-arp47601-p050.html |
| Name |
PA2G4 Antibody - C-terminal region (ARP47601_P050) |
| Protein Size (# AA) |
394 amino acids |
| Molecular Weight |
44kDa |
| NCBI Gene Id |
5036 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Proliferation-associated 2G4, 38kDa |
| Alias Symbols |
EBP1, HG4-1, p38-2G4 |
| Peptide Sequence |
Synthetic peptide located within the following region: LLQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQ |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Okada,M., (2007) J. Biol. Chem. 282 (50), 36744-36754 |
| Description of Target |
PA2G4 is an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells.This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Protein Interactions |
DHX9; PKN1; NPM1; NCL; LAMB1; HSPA1B; HNRNPA2B1; ACTB; ERBB3; DDX21; VIM; UBC; RNF20; SUMO2; SUMO3; MDM2; STUB1; HSPA4; YBX1; NMT1; MAP2; KRT17; FAU; RPL23A; RPS27L; EIF3K; DIMT1; NELFB; IGF2BP3; G3BP1; EXOSC5; HMGA2; HMGA1; EEF2K; UBL4A; ITGA4; FN1; IGF2 |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-PA2G4 (ARP47601_P050) antibody |
| Blocking Peptide |
For anti-PA2G4 (ARP47601_P050) antibody is Catalog # AAP47601 (Previous Catalog # AAPP28459) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human PA2G4 |
| Uniprot ID |
Q9UQ80 |
| Protein Name |
Proliferation-associated protein 2G4 |
| Sample Type Confirmation |
PA2G4 is strongly supported by BioGPS gene expression data to be expressed in HepG2 |
| Protein Accession # |
NP_006182 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_006191 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
PA2G4 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86% |
| Image 1 | Human HepG2
 | WB Suggested Anti-PA2G4 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysatePA2G4 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells |
|
| Image 2 | Human Fetal Brain
 | Host: Rabbit
Target Name: PA2G4
Sample Type: Human Fetal Brain
Antibody Dilution: 1.0ug/ml |
|
| Image 3 | Human Bronchial Epithelial Tissue
 | Rabbit Anti-PA2G4 Antibody
Catalog Number: ARP47601_P050
Formalin Fixed Paraffin Embedded Tissue: Human Bronchial Epithelial Tissue
Observed Staining: Cytoplasmic
Primary Antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
|
|
| Image 4 | Human Lung
 | Lung, respiratory epithelium |
|
