PA2G4 Peptide (AAP47601)

Data Sheet
 
Sku AAP47601
Old sku AAPP28459
Price $99.00
Name PA2G4 Peptide (AAP47601)
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Size 100 ug
Gene PA2G4
Alias symbols EBP1, HG4-1, p38-2G4
Gene id 5036
Description of target PA2G4 is an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells.This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot id Q9UQ80
Protein accession num NP_006182
Nucleotide accession num NM_006191
Protein size 394 amino acids
Molecular weight 44kDa
Application IHC, WB
Partner proteins ERBB3,HDAC2,AR,ERBB3,EXOSC5,HDAC2,PRKCA,PRKCB,PRKCG,RB1,SIN3A,SUMO4,AR,ATR,ERBB3,HDAC2,MTOR,RB1,SGK1,USP39
Quality control The peptide is characterized by mass spectroscopy
Key reference Okada,M., (2007) J. Biol. Chem. 282 (50), 36744-36754
Description This is a synthetic peptide designed for use in combination with anti-PA2G4 antibody (Catalog #: ARP47601_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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