| Product Number |
ARP30278_P050 |
| Product Page |
www.avivasysbio.com/bad-antibody-middle-region-arp30278-p050.html |
| Name |
BAD Antibody - middle region (ARP30278_P050) |
| Protein Size (# AA) |
168 amino acids |
| Molecular Weight |
18kDa |
| NCBI Gene Id |
572 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
BCL2-associated agonist of cell death |
| Alias Symbols |
BBC2, BCL2L8 |
| Peptide Sequence |
Synthetic peptide located within the following region: GAVEIRSRHSSYPAGTEDDEGMGEEPSPFRGRSRSAPPNLWAAQRYGREL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. |
| Protein Interactions |
BCL2L1; BCL2; AKT1; PAK1; BMH1; YWHAB; SFN; YWHAZ; RAF1; PRKACA; BRAF; ARAF; CREB3L3; STEAP3; YWHAQ; KEAP1; YWHAH; YWHAE; PRDX2; CDKN1A; VCP; SNCA; PPP1CA; BAX; SUMO2; YWHAG; PIM3; MCL1; RPS6KA5; PAK7; BCL2L10; WASF1; HRK; MAP2K5; BCL2L2; RPS6KA2; RPS6KA1 |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-BAD (ARP30278_P050) antibody |
| Blocking Peptide |
For anti-BAD (ARP30278_P050) antibody is Catalog # AAP30278 |
| Uniprot ID |
Q92934 |
| Protein Name |
Bcl2 antagonist of cell death |
| Publications |
Expression and localization of angiopoietin family in buffalo ovarian follicles during different stages of development and modulatory role of angiopoietins on steroidogenesis and survival of cultured buffalo granulosa cells. Theriogenology. 86, 1818-33 (2016). 27374424
Expression and localization of angiopoietin family in corpus luteum during different stages of oestrous cycle and modulatory role of angiopoietins on steroidogenesis, angiogenesis and survivability of cultured buffalo luteal cells. Reprod. Domest. Anim. 51, 855-869 (2016). 27569719 |
| Sample Type Confirmation |
BAD is strongly supported by BioGPS gene expression data to be expressed in 721_B |
| Protein Accession # |
NP_004313 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_004322 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
BAD |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | Human 721_B
 | WB Suggested Anti-BAD Antibody
Titration: 1.0 ug/ml
Positive Control: 721_B Whole CellBAD is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells |
|
| Image 2 | Human Hela Whole Cell
 | Host: Rabbit
Target Name: BAD
Sample Tissue: Human Hela Whole Cell
Antibody Dilution: 1ug/ml |
|
