| Product Number |
P100939_P050 |
| Product Page |
www.avivasysbio.com/id2-antibody-middle-region-p100939-p050.html |
| Name |
ID2 Antibody - middle region (P100939_P050) |
| Protein Size (# AA) |
134 amino acids |
| Molecular Weight |
15kDa |
| NCBI Gene Id |
3398 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| Description |
|
| Alias Symbols |
GIG8, ID2A, ID2H, bHLHb26 |
| Peptide Sequence |
Synthetic peptide located within the following region: TIVSLHHQRPGQNQASRTPLTTLNTDISILSLQASEFPSELMSNDSKALC |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Yang,J., (2008) Circ. Res. 102 (10), 1212-1221 |
| Description of Target |
ID2 belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation.The protein encoded by this gene belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene has been identified for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Protein Interactions |
ASB4; UBC; SUV39H2; PRMT6; KDM1A; SUV39H1; TCF12; TCF3; TSTA3; MAPK8; ID2; HSPA5; RBL2; RBL1; RB1; CDK2; USP1; MAPK3; MAPK1; E2F4; SIN3A; GATA4; NKX2-5; LRIF1; PPP1CA; RBM48; NEDD9; UNC119; MSC; TCF4; ELK3; ELK4; ELK1; PAX8; PAX5; PAX2; MYF6; MYF5; MYOG; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-ID2 (P100939_P050) antibody |
| Blocking Peptide |
For anti-ID2 (P100939_P050) antibody is Catalog # AAP31292 (Previous Catalog # AAPP02041) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human ID2 |
| Uniprot ID |
Q02363 |
| Protein Name |
DNA-binding protein inhibitor ID-2 |
| Protein Accession # |
NP_002157 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_002166 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
ID2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Pig |
| Application |
WB, IHC |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Human: 100%; Mouse: 100%; Pig: 92%; Rat: 100% |
| Image 1 | Human liver tissue
 | Rabbit Anti-ID2 Antibody
Catalog Number: P100939_P050
Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue
Observed Staining: Nucleus in hepatocytes
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
|
| Image 2 | Human Liver
 | Rabbit Anti-ID2 Antibody
Catalog Number: P100939_P050
Formalin Fixed Paraffin Embedded Tissue: Human Liver Tissue
Observed Staining: Cytoplasm
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec |
|
| Image 3 | Human Thymus
 | WB Suggested Anti-ID2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Human Thymus |
|
