ID2 Peptide - middle region (AAP31292)

Data Sheet
 
Sku AAP31292
Old sku AAPP02041
Price $99.00
Name ID2 Peptide - middle region (AAP31292)
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Size 100 ug
Gene ID2
Alias symbols GIG8, ID2A, ID2H, MGC26389, bHLHb26
Gene id 3398
Description of target ID2 belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation.The protein encoded by this gene belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene has been identified for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Swissprot id Q02363
Protein accession num NP_002157
Nucleotide accession num NM_002166
Protein size 134 amino acids
Molecular weight 15kDa
Application WB
Partner proteins ADD1,C1orf103,C7orf64,CDK2,ELK1,ELK3,ELK4,HES1,ID2,IFI16,MSC,MYF5,MYF6,MYOD1,MYOG,NEDD9,PAX2,PAX5,PAX8,PPP1CA,RB1,RBL1,RBL2,TCF12,TCF3,TCF4,UNC119,ADD1,BCAR1,C1orf103,C7orf64,ELSPBP1,MSC,MYF5,MYF6,MYOD1,NEDD9,TCF12,TCF3,TCF4,UNC119
Quality control The peptide is characterized by mass spectroscopy
Key reference Yang,J., (2008) Circ. Res. 102 (10), 1212-1221
Description This is a synthetic peptide designed for use in combination with anti-ID2 antibody (Catalog #: P100939_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Product format Lyophilized powder
Reconstitution and storage Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Lead time Domestic: within 24 hours delivery  International: 3-5 business days
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