| Product Number |
OAGA00688 |
| Product Page |
www.avivasysbio.com/klrc1-antibody-oaga00688.html |
| Name |
KLRC1 Antibody (OAGA00688) |
| Molecular Weight |
26 kDa |
| Isotype |
IgG |
| NCBI Gene Id |
3821 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.54 mg/ml |
| Gene Full Name |
NKG2-A/NKG2-B type II integral membrane protein |
| Alias Symbols |
NKG2, NKG2A, CD159A |
| Product Format |
Liquid |
| Reconstitution and Storage |
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-KLRC1 antibody - OAGA00688 |
| Additional Information |
Background: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq] |
| Additional Information |
Positive Controls: A431, HepG2 |
| Application Info |
Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000, ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Immunogen |
Synthetic peptide corresponding to a region within amino acids 1 and 45 of KLRC1 (Uniprot ID#P26715) |
| Additional Information |
Cellular Localization: Membrane; Single-pass type II membrane protein |
| Storage Buffer |
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Uniprot ID |
P26715 |
| Protein Name |
NKG2-A/NKG2-B type II integral membrane protein |
| Protein Accession # |
NP_002250.1 |
| Purification |
Purified by antigen-affinity chromatography. |
| Gene Symbol |
KLRC1 |
| Predicted Species Reactivity |
Human |
| Application |
ICC, IF, IHC-FFPE, WB |
| Image 1 | A431, HepG2
 | Sample (30 ug of whole cell lysate)
A: A431
B: Hep G2
12% SDS PAGE
NKG2-A (CD159a) antibody
OAGA00688 diluted at 1:1000
|
| | Image 2 | H1299 Xenograft
 | KLRC1 antibody [N1N2], N-term detects KLRC1 protein at cytosol on H1299 xenograft by immunohistochemical analysis.
Sample: Paraffin-embedded H1299 xenograft.
KLRC1 antibody [N1N2], N-term (OAGA00688) dilution: 1:500.
|
| | Image 3 | HeLa
 | Immunofluorescence analysis of methanol-fixed HeLa, using KLRC1(OAGA00688) antibody at 1:200 dilution. |
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