| Product Number |
OAAD00167 |
| Product Page |
www.avivasysbio.com/lama1-antibody-oaad00167.html |
| Name |
LAMA1 Antibody (OAAD00167) |
| Clone |
LAM-26 |
| Isotype |
IgG1 |
| NCBI Gene Id |
284217 |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Gene Full Name |
Laminin subunit alpha-1 |
| Alias Symbols |
LAMA, PTBHS, S-LAM-alpha |
| Product Format |
Liquid. PBS with 2 mg BSA and 0.01mg NaN3 as preservative. |
| Reference |
1. Zhang, X.; Vuolteenaho, R.; Tryggvason, K. : Structure of the human laminin alpha-2-chain gene (LAMA2), which is affected in congenital muscular dystrophy. J. Biol. Chem. 271: 27664-27669, 1996.
2. Ehrig, K.; Leivo, I.; Argraves, W. S.; Ruoslahti, E.; Engvall, E. : Merosin, a tissue-specific basement membrane protein, is a laminin-like protein. Proc. Nat. Acad. Sci. 87: 3264-3268, 1990.
3. Arahata, K.; Hayashi, Y. K.; Mizuno, Y.; Yoshida, M.; Ozawa, E. : Dystrophin-associated glycoprotein and dystrophin co-localisation at sarcolemma in Fukuyama congenital muscular dystrophy. (Letter) Lancet 342: 623-624, 1993. |
| Description of Target |
Laminin is a heterotrimeric extracellular matrix protein consisting of 3 chains: alpha-1, beta-1 and gamma-1, formerly called beta-2 (LAMA2). This gene is over 260, 000 base pairs and contains 64 exons. Laminin is similar with merosin, a basement membrane-associated protein found in placenta, striated muscle, and peripheral nerve, and both of them are members of the same family of basement membrane proteins. And merosin is the same as laminin M, a striated muscle-specific, basal-lamina-associated protein, it may play a primary role in the pathogenesis of that disorder. |
| Reconstitution and Storage |
At 4C for one month. It can also be aliquotted and stored frozen at -20C for longer time. |
| Datasheets/Manuals |
Printable datasheet for anti-LAMA1 (OAAD00167) antibody |
| Application Info |
WB: 0.25-0.5 ug/mL with appropriate system to detect laminin in cells and tissues.
IHC-P: 0.5-1 ug/mL to detect laminin formalin fixed and paraffin embedded tissues.
Optimal dilutions should be determined by end user. |
| Immunogen |
Human laminin. |
| Intended Use |
For research use only. |
| Uniprot ID |
P25391 |
| Protein Name |
Laminin subunit alpha-1 |
| Protein Accession # |
NP_005550.2 |
| Purification |
Purified by the goat anti-mouse IgG Affinity chromatography. |
| Nucleotide Accession # |
NM_005559.3 |
| Gene Symbol |
LAMA1 |
| Predicted Species Reactivity |
Human, Pig, feline |
| Application |
WB, IHC-P |
| Image 1 | |
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