Search Antibody, Protein, and ELISA Kit Solutions

LAMA1 Antibody (OAAD00167)

100 ug
$255.00
In Stock
Request Bulk Order Quote

Gene Symbol:
LAMA1
NCBI Gene Id:
284217
Official Gene Full Name:
Laminin subunit alpha-1
Protein Name:
Laminin subunit alpha-1
Swissprot Id:
P25391
Protein Accession #:
NP_005550.2
Nucleotide Accession #:
NM_005559.3
Replacement Item:
This antibody may replace item sc-37125 from Santa Cruz Biotechnology.
Description of Target:
Laminin is a heterotrimeric extracellular matrix protein consisting of 3 chains: alpha-1, beta-1 and gamma-1, formerly called beta-2 (LAMA2). This gene is over 260, 000 base pairs and contains 64 exons. Laminin is similar with merosin, a basement membrane-associated protein found in placenta, striated muscle, and peripheral nerve, and both of them are members of the same family of basement membrane proteins. And merosin is the same as laminin M, a striated muscle-specific, basal-lamina-associated protein, it may play a primary role in the pathogenesis of that disorder.
Host:
Mouse
Clonality:
Monoclonal
Purification:
Purified by the goat anti-mouse IgG Affinity chromatography.
Application:
WB, IHC-P
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express LAMA1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express LAMA1.
Immunogen:
Human laminin.
Predicted Species Reactivity:
Human, Pig, feline
Product Format:
Liquid. PBS with 2 mg BSA and 0.01mg NaN3 as preservative.
Reconstitution and Storage:
At 4C for one month. It can also be aliquotted and stored frozen at -20C for longer time.
Datasheets/Manuals:
Printable datasheet for anti-LAMA1 (OAAD00167) antibody
Clone:
LAM-26
Isotype:
IgG1
Application Info:
WB: 0.25-0.5 ug/mL with appropriate system to detect laminin in cells and tissues.
IHC-P: 0.5-1 ug/mL to detect laminin formalin fixed and paraffin embedded tissues.
Optimal dilutions should be determined by end user.
Intended Use:
For research use only.
Target Reference:
1. Zhang, X.; Vuolteenaho, R.; Tryggvason, K. : Structure of the human laminin alpha-2-chain gene (LAMA2), which is affected in congenital muscular dystrophy. J. Biol. Chem. 271: 27664-27669, 1996.
2. Ehrig, K.; Leivo, I.; Argraves, W. S.; Ruoslahti, E.; Engvall, E. : Merosin, a tissue-specific basement membrane protein, is a laminin-like protein. Proc. Nat. Acad. Sci. 87: 3264-3268, 1990.
3. Arahata, K.; Hayashi, Y. K.; Mizuno, Y.; Yoshida, M.; Ozawa, E. : Dystrophin-associated glycoprotein and dystrophin co-localisation at sarcolemma in Fukuyama congenital muscular dystrophy. (Letter) Lancet 342: 623-624, 1993.

Product Reviews

Protocol:
Tips Information:

Tell us what you think about this item!

Write A Review
    Please, wait...