Product Number |
OAAB17198 |
Product Page |
www.avivasysbio.com/tie-antibody-n-terminal-region-oaab17198.html |
Name |
TIE Antibody - N-terminal region (OAAB17198) |
Molecular Weight |
125090 Da |
Isotype |
Ig |
NCBI Gene Id |
7075 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
Approximately 0.5mg/ml. Actual concentration varies with each lot. |
Alias Symbols |
TIE, JTK14 |
Product Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Description of Target |
Purified Rabbit Polyclonal Antibody (Pab) |
Reconstitution and Storage |
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for OAAB17198 |
Additional Information |
Precautions: TIE Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Additional Information |
Function: Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis |
Application Info |
WB: 1:1000 IHC-P: 1:10~50 |
Immunogen |
This TIE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-42 amino acids from the N-terminal region of human TIE. |
Additional Information |
Cellular Location: Cell membrane; Single-pass type I membrane protein Tissue Location: Specifically expressed in developing vascular endothelial cells |
Uniprot ID |
P35590 |
Protein Name |
Tyrosine-protein kinase receptor Tie-1 |
Protein Accession # |
NP_005415.1 |
Gene Symbol |
TIE1 |
Predicted Species Reactivity |
Human, Mouse |
Application |
WB, IHC |
Predicted Homology Based on Immunogen Sequence |
Human; Mouse |
Image 1 | Mouse bladder
| Western blot analysis of anti-TIE Antibody (N-term) (Cat.# OAAB17198) in mouse bladder tissue lysates (35ug/lane). TIE(arrow) was detected using the purified Pab. |
| Image 2 | Human Brain
| Formalin-fixed and paraffin-embedded human brain tissue reacted with TIE antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
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