TIE Antibody - N-terminal region (OAAB17198)

Catalog No: OAAB17198

Size:400ul

Western blot analysis of anti-TIE Antibody (N-term) (Cat.# OAAB17198) in mouse bladder tissue lysates (35ug/lane). TIE(arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human brain tissue reacted with TIE antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB, IHC
• Additional Information: Precautions: TIE Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis
  Cellular Location: Cell membrane; Single-pass type I membrane protein
  Tissue Location: Specifically expressed in developing vascular endothelial cells
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This TIE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-42 amino acids from the N-terminal region of human TIE.
• Predicted Homology Based on Immunogen Sequence: Human; Mouse
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Application Info: WB: 1:1000
  IHC-P: 1:10~50

Target Info

• Gene Symbol: TIE1
• Alias Symbols: TIE, JTK14
• NCBI Gene Id: 7075
• Protein Name: Tyrosine-protein kinase receptor Tie-1
• Description of Target: Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: P35590
• Protein Accession #: NP_005415.1
• Molecular Weight: 125090 Da