KChIP3 Antibody - N-terminal region (Phospho-M1) (OAAB11394)

• Product Number: OAAB11394
• Name: KChIP3 Antibody - N-terminal region (Phospho-M1) (OAAB11394)
• Molecular Weight: 29231
• Isotype: Ig
• NCBI Gene Id: 30818
• Host: Rabbit
• Clonality: Polyclonal
• Concentration: 1.8 mg/ml
• Gene Full Name: potassium voltage-gated channel interacting protein 3
• Alias Symbols: A-type potassium channel modulatory protein 3;calsenilin;calsenilin, presenilin-binding protein, EF hand transcription factor;CSEN;DREAM;DRE-antagonist modulator;KCHIP3;Kv channel interacting protein 3, calsenilin;kv channel-interacting protein 3;potassium channel interacting protein 3.
• Product Format: Liquid. PBS with 0.09% (W/V) sodium azide.
• Description of Target: Calsenilin, calsenilin isoform 1 [Homo sapiens], calsenilin isoform 2 precursor [Homo sapiens]
• Reconstitution and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Additional Information: Cellular Location: Cytoplasm. Cell membrane; Lipid-anchor Endoplasmic reticulum. Golgi apparatus. Nucleus Note=Also membrane-bound, associated with the plasma membrane. In the presence of PSEN2 associated with the endoplasmic reticulum and Golgi. The sumoylated form is present only in the nucleus.
  Tissue Location: Highly expressed in brain. Widely expressed at lower levels. Expression levels are elevated in brain cortex regions affected by Alzheimer disease.
  
• Application Info: WB: 1:1000
  IHC-P: 1:50~100
  IF: 1:10~50
• Immunogen: This KChIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KChIP3.
• Intended Use: KChIP3 Antibody (N-term M1) is for research use only and not for use in diagnostic or therapeutic procedures.
• Uniprot ID: https://www.uniprot.org/uniprot/Q9Y2W7
• Protein Name: NP_001030086.1, NP_038462.1, Q9Y2W7
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_001030086.1,NP_038462.1
• Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Gene Symbol: KCNIP3
• Predicted Species Reactivity: Human, Mouse
• Application: Immunofluorescence, Immunohistochemistry-Paraffin, Western blot
• Image 1: Mouse Heart
  
  Western blot analysis of KChIP3 Antibody (N-term M1) (Cat.# OAAB11394) in mouse heart tissue lysates (35ug/lane). KChIP3(arrow) was detected using the purified Pab.
• Image 2: hepatocarcinoma
  
  Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
• Image 3: Human Brain
  
  Formalin-fixed and paraffin-embedded human brain tissue reacted with KChIP3 Antibody (N-term M1) (Cat.#OAAB11394), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
• Image 4: HepG2
  
  Confocal immunofluorescent analysis of KChIP3 Antibody (N-term M1) (Cat#OAAB11394) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).