| Product Number |
ARP75499_P050-FITC |
| Product Page |
www.avivasysbio.com/sun2-antibody-n-terminal-region-fitc-arp75499-p050-fitc.html |
| Name |
SUN2 Antibody - N-terminal region : FITC (ARP75499_P050-FITC) |
| Protein Size (# AA) |
717 amino acids |
| Molecular Weight |
78kDa |
| Conjugation |
FITC: Fluorescein Isothiocyanate |
| NCBI Gene Id |
25777 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Alias Symbols |
UNC84B |
| Peptide Sequence |
Synthetic peptide located within the following region: RSQRLTRYSQGDDDGSSSSGGSSVAGSQSTLFKDSPLRTLKRKSSNMKRL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
| Description of Target |
SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity. |
| Protein Interactions |
FBXW11; NRM; BTRC; UBC; WHSC1; RPS20; RAB5B; RAB5A; TP53BP1; C9orf3; SYNE1; SYNE2; AGO3; USP20; HGS; RAB5C; |
| Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Datasheets/Manuals |
Printable datasheet for anti-SUN2 (ARP75499_P050-FITC) antibody |
| Blocking Peptide |
For anti-SUN2 (ARP75499_P050-FITC) antibody is Catalog # AAP75499 |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N-terminal region of Human SUN2 |
| Uniprot ID |
Q9UH99 |
| Protein Accession # |
XP_005261558 |
| Purification |
Affinity purified |
| Gene Symbol |
SUN2 |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Image 1 | |
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