Product Number |
ARP75491_P050-FITC |
Product Page |
www.avivasysbio.com/prkd3-antibody-middle-region-fitc-arp75491-p050-fitc.html |
Name |
PRKD3 Antibody - middle region : FITC (ARP75491_P050-FITC) |
Protein Size (# AA) |
890 amino acids |
Molecular Weight |
97kDa |
Conjugation |
FITC: Fluorescein Isothiocyanate |
NCBI Gene Id |
23683 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
protein kinase D3 |
Alias Symbols |
EPK2, PKD3, PRKCN, PKC-NU, nPKC-NU |
Peptide Sequence |
Synthetic peptide located within the following region: GEVTFNGEPSSLGTDTDIPMDIDNNDINSDSSRGLDDTEEPSPPEDKMFF |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
Description of Target |
This gene belongs to the multigene protein kinase D family of serine/threonine kinases, which bind diacylglycerol and phorbol esters. Members of this family are characterized by an N-terminal regulatory domain comprised of a tandem repeat of cysteine-rich zinc-finger motifs and a pleckstrin domain. The C-terminal region contains the catalytic domain and is distantly related to calcium-regulated kinases. Catalytic activity of this enzyme promotes its nuclear localization. This protein has been implicated in a variety of functions including negative regulation of human airway epithelial barrier formation, growth regulation of breast and prostate cancer cells, and vesicle trafficking. |
Protein Interactions |
SKA2; UBC; DLAT; NUDT3; HDAC5; BCL6; IKBKG; RAE1; GSK3A; KPNB1; KPNA2; VAMP2; |
Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
Datasheets/Manuals |
Printable datasheet for anti-PRKD3 (ARP75491_P050-FITC) antibody |
Blocking Peptide |
For anti-PRKD3 (ARP75491_P050-FITC) antibody is Catalog # AAP75491 |
Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of Human KPCD3 |
Uniprot ID |
O94806 |
Protein Name |
serine/threonine-protein kinase D3 |
Protein Accession # |
XP_005264294 |
Purification |
Affinity purified |
Gene Symbol |
PRKD3 |
Predicted Species Reactivity |
Human |
Application |
WB |
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