| Product Number |
ARP74981_P050-FITC |
| Product Page |
www.avivasysbio.com/mdm2-antibody-middle-region-fitc-arp74981-p050-fitc.html |
| Name |
MDM2 Antibody - middle region : FITC (ARP74981_P050-FITC) |
| Protein Size (# AA) |
446 amino acids |
| Molecular Weight |
49kDa |
| Conjugation |
FITC: Fluorescein Isothiocyanate |
| NCBI Gene Id |
4193 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Alias Symbols |
HDMX, LSKB, hdm2, ACTFS |
| Peptide Sequence |
Synthetic peptide located within the following region: EISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKA |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer. |
| Reference |
N/A |
| Description of Target |
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. |
| Protein Interactions |
RPS7; RPS6; RPL26; UBE2D3; UBE2D2; UBE2D1; UBC; CDKN2A; HDAC1; TSC22D3; DAPK3; PARP1; PML; ARIH2; RPL23; KAT2B; AATF; RCHY1; DLAT; DHX9; DDX5; DAXX; U19; HRNR; OGDH; NCL; HNRNPM; MDM4; MDM2; ILF3; IFI16; IARS; HSP90AB1; HSP90AA1; HSPA8; HNRNPU; GTF2I; PER |
| Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Datasheets/Manuals |
Printable datasheet for anti-MDM2 (ARP74981_P050-FITC) antibody |
| Blocking Peptide |
For anti-MDM2 (ARP74981_P050-FITC) antibody is Catalog # AAP74981 |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of Human MDM2 |
| Uniprot ID |
Q00987-9 |
| Purification |
Affinity purified |
| Gene Symbol |
MDM2 |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Image 1 | |
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