RASA3 Antibody - N-terminal region : FITC (ARP74174_P050-FITC)

Data Sheet
 
Product Number ARP74174_P050-FITC
Product Page www.avivasysbio.com/rasa3-antibody-n-terminal-region-fitc-arp74174-p050-fitc.html
Name RASA3 Antibody - N-terminal region : FITC (ARP74174_P050-FITC)
Protein Size (# AA) 834 amino acids
Molecular Weight 91kDa
Conjugation FITC: Fluorescein Isothiocyanate
NCBI Gene Id 22821
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Alias Symbols GAPIII, GAP1IP4BP
Peptide Sequence Synthetic peptide located within the following region: YEAWYFLQPRDNGSKSLKPDDLGSLRLNVVYTEDHVFSSDYYSPLRDLLL
Product Format Liquid. Purified antibody supplied in 1x PBS buffer.
Description of Target The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.
Protein Interactions UBC; ARHGAP19; SPTB; APP; FES; RAP1A; GNB2L1; HCK;
Reconstitution and Storage All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Datasheets/Manuals Printable datasheet for anti-RASA3 (ARP74174_P050-FITC) antibody
Blocking Peptide For anti-RASA3 (ARP74174_P050-FITC) antibody is Catalog # AAP74174
Immunogen The immunogen is a synthetic peptide directed towards the N-terminal region of Human RASA3
Uniprot ID Q14644
Protein Accession # NP_031394
Purification Affinity Purified
Gene Symbol RASA3
Predicted Species Reactivity Human
Application WB
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