| Product Number |
ARP61726_P050 |
| Product Page |
www.avivasysbio.com/rpl7a-antibody-c-terminal-region-arp61726-p050.html |
| Name |
RPL7A Antibody - C-terminal region (ARP61726_P050) |
| Protein Size (# AA) |
266 amino acids |
| Molecular Weight |
29kDa |
| NCBI Gene Id |
6130 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
ribosomal protein L7a |
| Alias Symbols |
L7A, TRUP, SURF3 |
| Peptide Sequence |
Synthetic peptide located within the following region: KLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. This gene is included in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. It is co-transcribed with the U24, U36a, U36b, and U36c small nucleolar RNA genes, which are located in its second, fifth, fourth, and sixth introns, respectively. This gene rearranges with the trk proto-oncogene to form the chimeric oncogene trk-2h, which encodes an oncoprotein consisting of the N terminus of ribosomal protein L7a fused to the receptor tyrosine kinase domain of trk. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. |
| Protein Interactions |
HUWE1; UBC; TP53; SUMO2; CEP250; STAU1; MDM2; EED; RNF2; EEF1E1; AIMP1; DARS; RPL36; RPLP0; RPL26; RPL23A; RPL21; RPL15; RPL13; QARS; EIF2S1; TRAP1; PARK2; FBXO6; TARDBP; IGSF8; ICAM1; PAN2; SOCS3; UBL4A; VCAM1; ITGA4; FN1; CTBP2; MAGOH; EIF4A3; UPF1; ESR |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-RPL7A (ARP61726_P050) antibody |
| Blocking Peptide |
For anti-RPL7A (ARP61726_P050) antibody is Catalog # AAP61726 (Previous Catalog # AAPP47916) |
| Uniprot ID |
P62424 |
| Protein Name |
60S ribosomal protein L7a |
| Sample Type Confirmation |
RPL7A is supported by BioGPS gene expression data to be expressed in HEK293T |
| Protein Accession # |
NP_000963 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_000972 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
RPL7A |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
| Image 1 | Human 293T
 | WB Suggested Anti-RPL7A Antibody
Titration: 1.0 ug/ml
Positive Control: 293T Whole CellRPL7A is supported by BioGPS gene expression data to be expressed in HEK293T |
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